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An integrated approach to determine the abundance, mutation rate and phylogeny of the SARS-CoV-2 genome

29 Dec 2020

Abstract excerpt

The analysis of the SARS-CoV-2 genome datasets has significantly advanced our understanding of the biology and genomic adaptability of the virus. However, the plurality of advanced sequencing datasets-such as short and long reads-presents a formidable computational challenge to uniformly perform quantitative, variant or phylogenetic analysis, thus limiting its application in public health laboratories engaged in...

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PMID: 33479725
DOI: 10.1093/bib/bbaa437

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