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Mode and dynamics of vanA-type vancomycin resistance dissemination in Dutch hospitals

20 Jan 2021

Abstract excerpt

BACKGROUND: Enterococcus faecium is a commensal of the gastrointestinal tract of animals and humans but also a causative agent of hospital-acquired infections. Resistance against glycopeptides and to vancomycin has motivated the inclusion of E. faecium in the WHO global priority list. Vancomycin resistance can be conferred by the vanA gene cluster on the transposon Tn1546, which is frequently present in plasmids....

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PMID: 33472670
DOI: 10.1186/s13073-020-00825-3

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