Article
Gene expression pattern analysis using dual-color RT-MLPA and integrative genome-wide association studies of eQTL for tuberculosis suscepitibility.
Respiratory research - 20 Jan 2021
Ai Jing-Wen, Zhang Hanyue, Zhou Zumo, Weng Shanshan, Huang Heqing, Wang Sen, Shao Lingyun, Gao Yan, Wu Jing, Ruan Qiaoling, Wang Feifei, Jiang Ning, Chen Jiazhen, Zhang Wenhong
Abstract excerpt
BACKGROUND: When infected with Mycobacterium tuberculosis, only a small proportion of the population will develop active TB, and the role of host genetic factors in different TB infection status was not fully understood. METHODS: Forty-three patients with active tuberculosis and 49 with latent tuberculosis were enrolled in the prospective cohort. Expressing levels of 27 candidate mRNAs, which were previously...
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