Article
Single‐vesicle imaging and co‐localization analysis for tetraspanin profiling of individual extracellular vesicles
1 Jan 2021
Abstract excerpt
Extracellular vesicles (EVs) are secreted nano-sized vesicles that contain cellular proteins, lipids, and nucleic acids. Although EVs are expected to be biologically diverse, current analyses cannot adequately characterize this diversity because most are ensemble methods that inevitably average out information from diverse EVs. Here we describe a single vesicle analysis, which directly visualizes marker...
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