Article
Identifying extracellular vesicle populations from single cells.
Proceedings of the National Academy of Sciences of the United States of America - 21 Sept 2021
Nikoloff Jonas M, Saucedo-Espinosa Mario A, Kling André, Dittrich Petra S
Abstract excerpt
Extracellular vesicles (EVs) are constantly secreted from both eukaryotic and prokaryotic cells. EVs, including those referred to as exosomes, may have an impact on cell signaling and an incidence in diseased cells. In this manuscript, a platform to capture, quantify, and phenotypically classify the EVs secreted from single cells is introduced. Microfluidic chambers of about 300 pL are employed to trap and...
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