MiR-133a-3p Relieves the Oxidative Stress Induced Trophoblast Cell Apoptosis Through the BACH1/Nrf2/HO-1 Signaling Pathway

Abstract excerpt

Preeclampsia (PE) is a major cause of the pregnancy morbidity and mortality over the world. Disorganized placentation caused by trophoblast cell abnormity is one of main risk factors to induce PE. MiR-133a-3p has been shown to contain regulatory effects on oxidative stress in the cardiomyocytes. But the effects of miR-133a-3p on oxidative stress-induced apoptosis in the trophoblast cells remain unknown. In this...

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