Article
Mycoplasma genitalium infections can comprise a mixture of both fluoroquinolone-susceptible and fluoroquinolone-resistant strains.
The Journal of antimicrobial chemotherapy - 12 Mar 2021
Sweeney Emma L, Lowry Kym, Bletchly Cheryl, Nimmo Graeme R, Whiley David M
Abstract excerpt
BACKGROUND: Mycoplasma genitalium was recently added to the CDC's antimicrobial resistance threats 'watch list', as it has rapidly become resistant to mainstay treatments. In Australia, treatment failure with fluoroquinolones remain commonplace, even when Sanger sequencing fails to identify evidence of resistance mutations. METHODS: Suspecting that Sanger sequencing may miss low-load mixed infections, we applied...
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