Article
Availability of the Molecular Switch XylR Controls Phenotypic Heterogeneity and Lag Duration during Escherichia coli Adaptation from Glucose to Xylose.
mBio - 22 Dec 2020
Barthe Manon, Tchouanti Josué, Gomes Pedro Henrique, Bideaux Carine, Lestrade Delphine, Graham Carl, Steyer Jean-Philippe, Meleard Sylvie, Harmand Jérôme, Gorret Nathalie, Cocaign-Bousquet Muriel, Enjalbert Brice
Abstract excerpt
The glucose-xylose metabolic transition is of growing interest as a model to explore cellular adaption since these molecules are the main substrates resulting from the deconstruction of lignocellulosic biomass. Here, we investigated the role of the XylR transcription factor in the length of the lag phases when the bacterium Escherichia coli needs to adapt from glucose- to xylose-based growth. First, a variety of...
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