Article
The overlap of genetic susceptibility to schizophrenia and cardiometabolic disease can be used to identify metabolically different groups of individuals.
Scientific reports - 12 Jan 2021
Strawbridge Rona J, Johnston Keira J A, Bailey Mark E S, Baldassarre Damiano, Cullen Breda, Eriksson Per, deFaire Ulf, Ferguson Amy, Gigante Bruna, Giral Philippe, Graham Nicholas, Hamsten Anders, Humphries Steve E, Kurl Sudhir, Lyall Donald M, Lyall Laura M, Pell Jill P, Pirro Matteo, Savonen Kai, Smit Andries J, Tremoli Elena, Tomainen Tomi-Pekka, Veglia Fabrizio, Ward Joey, Sennblad Bengt, Smith Daniel J
Abstract excerpt
Understanding why individuals with severe mental illness (Schizophrenia, Bipolar Disorder and Major Depressive Disorder) have increased risk of cardiometabolic disease (including obesity, type 2 diabetes and cardiovascular disease), and identifying those at highest risk of cardiometabolic disease are important priority areas for researchers. For individuals with European ancestry we explored whether genetic...
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