Article
Divergence in phenotyping and genotyping analysis of the Lewis histo-blood group system.
Transfusion medicine (Oxford, England) - 1 Apr 2021
Donta Ajaykumar, Gorakshakar Ajit C, Ghosh Kanjaksha
Abstract excerpt
OBJECTIVES: This study evaluated the red blood cell (RBC) Lewis phenotypes by simple haemagglutination technique and molecular genotyping in healthy individuals. BACKGROUND: The expression of Lewis antigen on RBCs is dependent on the interaction of FUT3 and FUT2 genes. Complexity of the genetic control of Lewis antigen expression and the error-prone nature of Lewis phenotyping result in non-genuine RBC Lewis...
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