Article
Psychiatric symptoms and syndromes transcending diagnostic boundaries in Indian multiplex families: The cohort of ADBS study.
Psychiatry research - 1 Feb 2021
Sreeraj Vanteemar S, Holla Bharath, Ithal Dhruva, Nadella Ravi Kumar, Mahadevan Jayant, Balachander Srinivas, Ali Furkhan, Sheth Sweta, Narayanaswamy Janardhanan C, Venkatasubramanian Ganesan, John John P, Varghese Mathew, Benegal Vivek, Jain Sanjeev, Reddy Yc Janardhan, Viswanath Biju
Abstract excerpt
Syndromes of schizophrenia, bipolar disorder, obsessive-compulsive disorder, substance use disorders and Alzheimer's dementia are highly heritable. About 10-20% of subjects have another affected first degree relative (FDR), and thus represent a 'greater' genetic susceptibility. We screened 3583 families to identify 481 families with multiple affected members, assessed 1406 individuals in person, and collected...
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