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Article

Prognostic mutation constellations in acute myeloid leukaemia and myelodysplastic syndrome.

Current opinion in hematology - 1 Mar 2021

Iacobucci Ilaria, Mullighan Charles G

Abstract excerpt

PURPOSE OF REVIEW: In the past decade, numerous studies analysing the genome and transcriptome of large cohorts of acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS) patients have substantially improved our knowledge of the genetic landscape of these diseases with the identification of heterogeneous constellations of germline and somatic mutations with prognostic and therapeutic relevance. However,...

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Identifiers

PMID: 33427759
DOI: 10.1097/MOH.0000000000000629
PMCID: PMC8174569

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