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SLC35F2, a Transporter Sporadically Mutated in the Untranslated Region, Promotes Growth, Migration, and Invasion of Bladder Cancer Cells.

Cells - 6 Jan 2021

Kotolloshi Roland, Hölzer Martin, Gajda Mieczyslaw, Grimm Marc-Oliver, Steinbach Daniel

Abstract excerpt

Bladder cancer is a very heterogeneous disease and the molecular mechanisms of carcinogenesis and progression are insufficiently investigated. From the DNA sequencing analysis of matched non-muscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC) samples from eight patients, we identified the tumour-associated gene SLC35F2 to be mutated in the 5' and 3' untranslated region (UTR). One...

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PMID: 33418944
DOI: 10.3390/cells10010080
PMCID: PMC7825079

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