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Article

Donor-specific phenotypic variation in hiPSC cardiomyocyte-derived exosomes impacts endothelial cell function.

American journal of physiology. Heart and circulatory physiology - 1 Mar 2021

Turner Amy, Aggarwal Praful, Matter Andrea, Olson Benjamin, Gu C Charles, Hunt Steven C, Lewis Cora E, Arnett Donna K, Lorier Rachel, Broeckel Ulrich

Abstract excerpt

Exosomes are an important mechanism of cell-cell interaction in the cardiovascular system, both in maintaining homeostasis and in stress response. Interindividual differences that alter content in exosomes may play a role in cardiovascular disease pathology. To study the effect of interindividual cardiomyocyte (CM) variation, we characterized exosomal content in phenotypically diverse human induced pluripotent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hypertrophy, Left Ventricular

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Source

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Identifiers

PMID: 33416449
DOI: 10.1152/ajpheart.00463.2020
PMCID: PMC8294700

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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