Article
Phylogenetic and functional diversity of aldehyde-alcohol dehydrogenases in microalgae.
Plant molecular biology - 1 Mar 2021
van Lis Robert, Couté Yohann, Brugière Sabine, Tourasse Nicolas J, Laurent Benoist, Nitschke Wolfgang, Vallon Olivier, Atteia Ariane
Abstract excerpt
KEY MESSAGE: The study shows the biochemical and enzymatic divergence between the two aldehyde-alcohol dehydrogenases of the alga Polytomella sp., shedding light on novel aspects of the enzyme evolution amid unicellular eukaryotes. Aldehyde-alcohol dehydrogenases (ADHEs) are large metalloenzymes that typically perform the two-step reduction of acetyl-CoA into ethanol. These enzymes consist of an N-terminal...
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