Article
Association between BDNF rs6265 polymorphisms and postoperative cognitive dysfunction in Chinese Han Population.
Brain and behavior - 1 Oct 2020
Xie Songhui, Yu Lu, Zhou Mingming, Liu Li, Lei Daoyun, Han Chao
Abstract excerpt
INTRODUCTION: Brain-derived neurotrophic factor (BDNF) plays a critical role in the pathogenesis of postoperative cognitive dysfunction (POCD). In present study, we aimed to assess the possible association between POCD and BDNF rs6265 polymorphisms. METHODS: 124 patients aged 60 years or older scheduled for elective surgery under general anesthesia and 25 age- and gender-matched healthy volunteers were recruited....
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