Article
Reconstructing Genotypes in Private Genomic Databases from Genetic Risk Scores.
Journal of computational biology : a journal of computational molecular cell biology - 1 May 2021
Paige Brooks, Bell James, Bellet Aurélien, Gascón Adrià, Ezer Daphne
Abstract excerpt
Some organizations such as 23andMe and the UK Biobank have large genomic databases that they re-use for multiple different genome-wide association studies. Even research studies that compile smaller genomic databases often utilize these databases to investigate many related traits. It is common for the study to report a genetic risk score (GRS) model for each trait within the publication. Here, we show that under...
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