Article
Exploration of genetic factors resulting in abnormal disease in cattle experimentally challenged with bovine spongiform encephalopathy.
Prion - 1 Dec 2021
Dudas Sandor, Anderson Renee, Staskevicus Antanas, Mitchell Gordon, Cross James C, Czub Stefanie
Abstract excerpt
Since the discovery of bovine spongiform encephalopathy (BSE), researchers have orally challenged cattle with infected brain material to study various aspects of disease pathogenesis. Unlike most other pathogens, oral BSE challenge does not always result in the expected clinical presentation and pathology. In a recent study, steers were challenged orally with BSE and all developed clinical signs and were...
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