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Article

De novo ZIC2 frameshift variant associated with frontonasal dysplasia in a Limousin calf

2 Jan 2021

Abstract excerpt

BACKGROUND: Bovine frontonasal dysplasias like arhinencephaly, synophthalmia, cyclopia and anophthalmia are sporadic congenital facial malformations. In this study, computed tomography, necropsy, histopathological examinations and whole genome sequencing on an Illumina NextSeq500 were performed to characterize a stillborn Limousin calf with frontonasal dysplasia. In order to identify private genetic and...

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PMID: 33388042
DOI: 10.1186/s12864-020-07350-y

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