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Article

Changes in IgA-targeted microbiota following fecal transplantation for recurrent Clostridioides difficile infection

31 Dec 2020

Abstract excerpt

Secretory immunoglobulin A (IgA) interacts with intestinal microbiota and promotes mucosal homeostasis. IgA-bacteria interactions are altered during inflammatory diseases, but how these interactions are shaped by bacterial, host, and environmental factors remains unclear. In this study, we utilized IgA-SEQ to profile IgA-bound fecal bacteria in 48 recurrent Clostridioides difficile patients before and after...

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PMID: 33382360
DOI: 10.1080/19490976.2020.1862027

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