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Article

Clinical implications of plasma ctDNA features and dynamics in gastric cancer treated with HER2‐targeted therapies

1 Dec 2020

Abstract excerpt

BACKGROUND: Gastric cancer (GC) is confronted with limited options for precision medicine. Human epidermal growth factor receptor 2 (HER2) is the principal druggable target of GC, yet proper biomarkers for response/resistance prediction remain unveiled. METHODS: From 40 GC patients received HER2-targeted therapy, a total of 327 peripheral blood plasma specimens was collected including baseline and treatment time...

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PMID: 33377634
DOI: 10.1002/ctm2.254

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