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Niraparib as Maintenance Therapy in Germline ATM-mutated and Somatic BRCA2-mutated Ovarian Cancer with Brain Metastases: A Case Report and Literature Review

1 Dec 2020

Abstract excerpt

Abstract: Brain metastases from epithelial ovarian cancer are very rare with an incidence of only 1– 2.5%. Many therapeutic methods such as surgery, irradiation and chemotherapy do produce survival benefits, but the overall outcome remains unsatisfactory. The BRCA (breast cancer susceptibility gene) mutation status seems to be associated with the development of brain metastases from ovarian cancer and these...

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PMID: 33376347
DOI: 10.2147/ott.s281302

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Niraparib as Maintenance Therapy in Germline ATM-mutated and Somatic BRCA2-mutated Ovarian Cancer with Brain Metastases: A Case Report and Literature ReviewPMID 33376347Read ↗

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