Article
Niraparib as a therapeutic agent for the treatment of ovarian cancer meningeal dissemination with BRCA1 mutation.
The journal of obstetrics and gynaecology research - 1 Jul 2023
Nei Takashi, Tamauchi Satoshi, Ikeda Yoshiki, Yoshikawa Nobuhisa, Niimi Kaoru, Kajiyama Hiroaki
Abstract excerpt
This study analyzed a 63-year-old woman with hereditary BRCA1 mutation. She underwent interval debulking surgery after neoadjuvant chemotherapy for high-grade serous ovarian carcinoma (HGSOC). After 2 years of postoperative chemotherapy, she developed headache and dizziness, and a suspected metastatic cerebellar mass in left ovary was detected. Pathological analysis of the mass revealed HGSOC, which was removed...
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