Article
A cross-eyed geneticist's view VI. Segregation distortion in Drosophila melanogaster: Recent progress in solving 'an esoteric puzzle'.
Journal of biosciences - 1 Jan 2020
Kasbekar Durgadas P
Abstract excerpt
Segregation distortion refers to an unusual genetic phenomenon in diploid organisms by which the two alleles at a locus in a parent are not recovered in the classical 1:1 Mendelian ratio in its offspring. The Drosophila melanogaster neogene Sd was created by a duplication breakpoint on the left arm of chromosome 2 (2L), and encodes a truncated RanGAP protein with normal GTPase activity but which mis-localizes to...
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