Article
The genotype distribution, infection stage and drug resistance mutation profile of human immunodeficiency virus-1 among the infected blood donors from five Chinese blood centers, 2014-2017.
PloS one - 1 Jan 2020
Liang Shan, Liu Zhiyang, Wang Shaoli, Liu Jing, Shi Ling, Mao Wei, Liu Cunxu, Wan Jianhua, Zhu Lili, Huang Mei, Liu Yu, Wang Jingxing, Ness Paul, Shan Hua, Zeng Peibin, He Miao
Abstract excerpt
Human immunodeficiency virus-1 (HIV-1) exhibits high diversity and complexity in China, challenging the disease surveillance and antiretroviral therapy. Between July 1, 2014 and January 30, 2017, we investigated the profiles of HIV-1 infection stages, genotype distribution and drug resistance mutations (DRMs) using plasma samples from HIV Western blot (WB) confirmed blood donors from five Chinese blood centers...
Topics
- Adult
- Anti-HIV Agents
- Blood Donors
- China
- Drug Resistance, Viral
- Genotype
- Genotyping Techniques
- HIV Infections
- HIV Protease
- HIV-1