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Mechanisms involved in the adaptation of Escherichia coli O157:H7 to the host intestinal microenvironment.

Clinical science (London, England : 1979) - 23 Dec 2020

Fernandez-Brando Romina J, McAteer Sean P, Montañez-Culma Johanna, Cortés-Araya Yennifer, Tree Jai, Bernal Alan, Fuentes Federico, Fitzgerald Stephen, Pineda Gonzalo E, Ramos M Victoria, Gally David L, Palermo Marina S

Abstract excerpt

Host adaptation of pathogens may increase intra- and interspecies transmission. We showed previously that the passage of a clinically isolated enterohemorrhagic Escherichia coli (EHEC) O157 strain (125/99) through the gastrointestinal tract of mice increases its pathogenicity in the same host. In this work, we aimed to elucidate the underlying mechanism(s) involved in the patho-adaptation of the stool-recovered...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33346356
DOI: 10.1042/CS20200971

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