Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to the Mediterranean diet pattern is low.

doi:10.1186/1475-2840-11-137

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Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to the Mediterranean diet pattern is low.

Cardiovascular diabetology - 6 Nov 2012

Ortega-Azorín Carolina, Sorlí Jose V, Asensio Eva M, Coltell Oscar, Martínez-González Miguel Ángel, Salas-Salvadó Jordi, Covas Maria-Isabel, Arós Fernando, Lapetra José, Serra-Majem Lluís, Gómez-Gracia Enrique, Fiol Miquel, Sáez-Tormo Guillermo, Pintó Xavier, Muñoz Miguel Angel, Ros Emilio, Ordovás Jose M, Estruch Ramon, Corella Dolores

Abstract excerpt

BACKGROUND: Although the fat mass and obesity (FTO) and melanocortin-4 receptor (MC4R) genes have been consistently associated with obesity risk, the association between the obesity-risk alleles with type 2 diabetes is still controversial. In some recent meta-analyses in which significant results...

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PMID: 23130628
DOI: 10.1186/1475-2840-11-137
PMCID: PMC3495759

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23130628-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

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