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Article

Solitary subependymal giant cell astrocytoma: Case report and review of the literature.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Dec 2020

Corlette Lucy, Reid Amy, Roberts-Thomson Samuel, Christie Michael, Gaillard Frank

Abstract excerpt

Tuberous sclerosis complex (TSC) is a multisystem autosomal dominant hamartoma syndrome caused by mutations in TSC1 or TSC2 genes, leading to upregulation of cell growth signalling pathways. Subependymal giant cell astrocytomas (SEGAs) are seen almost exclusively in TSC patients. We report a 'solitary SEGA' in an adult patient, with confirmed deletion of the entire TSC2 gene on tumour tissue DNA, in the absence...

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Identifiers

PMID: 33317733
DOI: 10.1016/j.jocn.2020.10.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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