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Perturbations of the gut microbiome in anti-CCP positive individuals at risk of developing rheumatoid arthritis

26 Nov 2020

Abstract excerpt

OBJECTIVE: Individuals with newly diagnosed RA have a distinct microbiome when compared with healthy controls. However, little is known as to when these microbiome perturbations begin. Using a prospective at-risk cohort of individuals positive for anti-citrullinated protein (anti-CCP) antibody with new onset musculoskeletal symptoms, but without clinical arthritis, we investigated for the presence of a gut...

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PMID: 33313854
DOI: 10.1093/rheumatology/keaa792

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