Article
Impaired secretion of platelet granules in patients with Duchenne muscular dystrophy - results of a prospective diagnostic study.
Neuromuscular disorders : NMD - 1 Jan 2021
Schorling D C, Müller C K, Pechmann A, Borell S, Rosenfelder S, Kölbel H, Schara U, Zieger B, Kirschner J
Abstract excerpt
A tendency to bleed during scoliosis surgery has been reported repeatedly in Duchenne muscular dystrophy (DMD) and diagnostic studies show a prolonged bleeding time. The pathophysiological background is still not fully understood. The short dystrophin isoform dp71 is expressed in platelets and mediates contractile properties. We performed a bicentric, non-blinded, prospective diagnostic study in 53 patients with...
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