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Article

The SARS-CoV-2 ORF10 is not essential in vitro or in vivo in humans.

PLoS pathogens - 1 Dec 2020

Pancer Katarzyna, Milewska Aleksandra, Owczarek Katarzyna, Dabrowska Agnieszka, Kowalski Michał, Łabaj Paweł P, Branicki Wojciech, Sanak Marek, Pyrc Krzysztof

Abstract excerpt

SARS-CoV-2 genome annotation revealed the presence of 10 open reading frames (ORFs), of which the last one (ORF10) is positioned downstream of the N gene. It is a hypothetical gene, which was speculated to encode a 38 aa protein. This hypothetical protein does not share sequence similarity with any other known protein and cannot be associated with a function. While the role of this ORF10 was proposed, there is...

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Identifiers

PMID: 33301543
DOI: 10.1371/journal.ppat.1008959
PMCID: PMC7755277

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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