Article
Normal activated partial thromboplastin time in Chinese patients with mild hemophilia B.
Hematology (Amsterdam, Netherlands) - 1 Dec 2020
Wang Xiong, Tang Ning, Shen Na, Zhu Yaowu, Lu Yanjun, Gao Linna
Abstract excerpt
OBJECTIVES: Hemophilia B (HB, OMIM: 300746) is one of the most common bleeding disorders with an X-linked recessive inheritance pattern, caused by the deficiency of coagulation factor IX (FIX). FIX is encoded by the F9 gene located on Xq27.1. Diagnosis of HB is primarily suspected by prolonged activated partial thromboplastin time (APTT), decreased FIX activity (FIX:C) or genetic test of the F9 gene. We herein...
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