Article
Essential Role for FtsL in Activation of Septal Peptidoglycan Synthesis.
mBio - 8 Dec 2020
Park Kyung-Tae, Du Shishen, Lutkenhaus Joe
Abstract excerpt
Spatiotemporal regulation of septal peptidoglycan (PG) synthesis is achieved by coupling assembly and activation of the synthetic enzymes (FtsWI) to the Z ring, a cytoskeletal element that is required for division in most bacteria. In Escherichia coli, the recruitment of the FtsWI complex is dependent upon the cytoplasmic domain of FtsL, a component of the conserved FtsQLB complex. Once assembled, FtsWI is...
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