Article
Complete remission of heavily treated ovarian clear cell carcinoma with ARID1A mutations after pembrolizumab and bevacizumab combination therapy: a case report.
Journal of ovarian research - 8 Dec 2020
Lin Yu-Chien, Wen Kuo-Chang, Sung Pi-Lin, Chou Yu-Ting, Liew Phui-Ly, Chen Lin-Yu, Huang Rui-Lan, Lai Hung-Cheng, Chang Lu-Te
Abstract excerpt
BACKGROUND: Patients with ovarian clear cell carcinoma (OCCC) have a poor prognosis because they show low sensitivity to platinum-based chemotherapy. New treatments for refractory OCCC are urgently needed. CASE PRESENTATION: We present a patient with refractory OCCC in whom conventional chemotherapy failed. Cachexia was induced by the disseminating recurrent tumors. Tumor tissue staining and genomic analysis...
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