Article
Shared susceptibility loci at 2q33 region for lung and esophageal cancers in high-incidence areas of esophageal cancer in northern China.
PloS one - 1 Jan 2017
Zhao Xue Ke, Mao Yi Min, Meng Hui, Song Xin, Hu Shou Jia, Lv Shuang, Cheng Rang, Zhang Tang Juan, Han Xue Na, Ren Jing Li, Qi Yi Jun, Wang Li Dong
Abstract excerpt
BACKGROUND: Cancers from lung and esophagus are the leading causes of cancer-related deaths in China and share many similarities in terms of histological type, risk factors and genetic variants. Recent genome-wide association studies (GWAS) in Chinese esophageal cancer patients have demonstrated six high-risk candidate single nucleotide polymorphisms (SNPs). Thus, the present study aimed to determine the risk of...
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