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Article

Untangling a Gordian knot: the role of a GluCl3 I321T mutation in abamectin resistance in Tetranychus urticae.

Pest management science - 1 Apr 2021

Xue Wenxin, Mermans Catherine, Papapostolou Kyriaki-Maria, Lamprousi Mantha, Christou Iason-Konstantinos, Inak Emre, Douris Vassilis, Vontas John, Dermauw Wannes, Van Leeuwen Thomas

Abstract excerpt

BACKGROUND: The cys-loop ligand-gated ion channels, including the glutamate-gated chloride channel (GluCl) and GABA-gated chloride channel (Rdl) are important targets for drugs and pesticides. The macrocyclic lactone abamectin primarily targets GluCl and is commonly used to control the spider mite Tetranychus urticae, an economically important crop pest. However, abamectin resistance has been reported for...

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PMID: 33283957
DOI: 10.1002/ps.6215

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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