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Article

Th2 Biased Immunity With Altered B Cell Profiles in Circulation of Patients With Sporotrichosis Caused by Sporothrix globosa.

Frontiers in immunology - 1 Jan 2020

Zu Jianjiao, Yao Lei, Song Yang, Cui Yan, Guan Mengqi, Chen Ruili, Zhen Yu, Li Shanshan

Abstract excerpt

Sporotrichosis is a subcutaneous mycotic infection, and Sporothrixglobosa is one of the causative agents with a worldwide distribution, notably in Asia. However, the immune profile in human sporotrichosis caused by S. globosa still remains obscure. Here, we demonstrated enhanced Th2 response in circulation with significant increases in Th2 frequency, Th2/Tregs as well as IL-4 seretion in patients. Elevated...

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Identifiers

PMID: 33281813
DOI: 10.3389/fimmu.2020.570888
PMCID: PMC7691245

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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