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Article

Aberrant upregulation of CaSR promotes pathological new bone formation in ankylosing spondylitis

1 Dec 2020

Abstract excerpt

Pathological new bone formation is a typical pathological feature in ankylosing spondylitis (AS), and the underlying molecular mechanism remains elusive. Previous studies have shown that the calcium-sensing receptor (CaSR) is critical for osteogenic differentiation while also being highly involved in many inflammatory diseases. However, whether it plays a role in pathological new bone formation of AS has not been...

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PMID: 33259138
DOI: 10.15252/emmm.202012109

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