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SARS-CoV-2 genomic and subgenomic RNAs in diagnostic samples are not an indicator of active replication

27 Nov 2020

Abstract excerpt

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was first detected in late December 2019 and has spread worldwide. Coronaviruses are enveloped, positive sense, single-stranded RNA viruses and employ a complicated pattern of virus genome length RNA replication as well as transcription of genome length and leader containing subgenomic RNAs. Although not fully understood, both replication and...

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PMID: 33247099
DOI: 10.1038/s41467-020-19883-7

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