Article
Notch Signaling Regulation in Autoinflammatory Diseases.
International journal of molecular sciences - 23 Nov 2020
Gratton Rossella, Tricarico Paola Maura, d'Adamo Adamo Pio, Bianco Anna Monica, Moura Ronald, Agrelli Almerinda, Brandão Lucas, Zupin Luisa, Crovella Sergio
Abstract excerpt
Notch pathway is a highly conserved intracellular signaling route that modulates a vast variety of cellular processes including proliferation, differentiation, migration, cell fate and death. Recently, the presence of a strict crosstalk between Notch signaling and inflammation has been described, although the precise molecular mechanisms underlying this interplay have not yet been fully unravelled. Disruptions in...
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