Article
Polymorphisms and expression pattern of circular RNA circ-ITCH contributes to the carcinogenesis of hepatocellular carcinoma.
Oncotarget - 18 Jul 2017
Guo Wenzhi, Zhang Jiakai, Zhang Dongyu, Cao Shengli, Li Gongquan, Zhang Shuijun, Wang Zhihui, Wen Peihao, Yang Han, Shi Xiaoyi, Pan Jie, Ye Hua
Abstract excerpt
Hepatocellular carcinoma (HCC) ranks the sixth most common cancer and the third cause of cancer-related mortality worldwide. Recent studies identified that circ-ITCH Suppresses mutiple cancers proliferation via inhibiting the Wnt/beta-Catenin pathway. In current study, conducted a genetic association study together with epidemiological follow-up study to delineate the role of circ-ITCH in the development and...
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