Article
Transcriptome profiling in adult attention-deficit hyperactivity disorder.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Dec 2020
Mortimer Niall, Sánchez-Mora Cristina, Rovira Paula, Vilar-Ribó Laura, Richarte Vanesa, Corrales Montse, Fadeuilhe Christian, Rivero Olga, Lesch Klaus-Peter, Casas Miguel, Ramos-Quiroga Josep Antoni, Artigas María Soler, Ribasés Marta
Abstract excerpt
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder with an estimated heritability of around 70%. Although the largest genome-wide association study (GWAS) meta-analysis on ADHD identified independent loci conferring risk to the disorder, the molecular mechanisms underlying the genetic basis of the disorder remain to be elucidated. To explore ADHD biology, we ran a two-step...
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