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Article

Astaxanthin Counteracts Vascular Calcification In Vitro Through an Early Up-Regulation of SOD2 Based on a Transcriptomic Approach.

International journal of molecular sciences - 12 Nov 2020

Chao Chia-Ter, Yeh Hsiang-Yuan, Tsai You-Tien, Yuan Tzu-Hang, Liao Min-Tser, Huang Jenq-Wen, Chen Huei-Wen

Abstract excerpt

Vascular calcification (VC) is a critical contributor to the rising cardiovascular risk among at-risk populations such as those with diabetes or renal failure. The pathogenesis of VC involves an uprising of oxidative stress, for which antioxidants can be theoretically effective. However, astaxanthin, a potent antioxidant, has not been tested before for the purpose of managing VC. To answer this question, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33198315
DOI: 10.3390/ijms21228530
PMCID: PMC7698184

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