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Article

The Genetic Architecture of High Bone Mass.

Frontiers in endocrinology - 1 Jan 2020

Gregson Celia L, Duncan Emma L

Abstract excerpt

The phenotypic trait of high bone mass (HBM) is an excellent example of the nexus between common and rare disease genetics. HBM may arise from carriage of many 'high bone mineral density [BMD]'-associated alleles, and certainly the genetic architecture of individuals with HBM is enriched with high BMD variants identified through genome-wide association studies of BMD. HBM may also arise as a monogenic skeletal...

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Identifiers

PMID: 33193107
DOI: 10.3389/fendo.2020.595653
PMCID: PMC7658409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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