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The Regulation of Ferroptosis by Tumor Suppressor p53 and its Pathway

9 Nov 2020

Abstract excerpt

Tumor suppressor p53 plays a key role in tumor suppression. In addition to tumor suppression, p53 is also involved in many other biological and pathological processes, such as immune response, maternal reproduction, tissue ischemia/reperfusion injuries and neurodegenerative diseases. While it has been widely accepted that the role of p53 in regulation of cell cycle arrest, senescence and apoptosis contributes...

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PMID: 33182266
DOI: 10.3390/ijms21218387

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