Article
GenSeizer: a Multiplex PCR-Based Targeted Gene Sequencing Platform for Rapid and Accurate Identification of Major Mycobacterium Species.
Journal of clinical microbiology - 21 Jan 2021
Li Bing, Xu Liyun, Guo Qi, Chen Jianhui, Zhang Yanan, Huang Wenpan, Zhang Zhemin, Han Lizhong, Xu Xiaogang, Chu Haiqing
Abstract excerpt
Mycobacterium tuberculosis and nontuberculous mycobacterium (NTM) infections often exhibit similar clinical symptoms. Timely and effective treatment relies on the rapid and accurate identification of species and resistance genotypes. In this study, a new platform (GenSeizer), which combines bioinformatics analysis of a large data set and multiplex PCR-based targeted gene sequencing, was developed to identify 10...
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