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In Vitro Meiosis of Male Germline Stem Cells

1 Nov 2020

Abstract excerpt

In vitro spermatogenesis has been achieved by culturing mouse embryonic stem cells (ESCs) together with a cell suspension of male juvenile gonad. However, for human fertility treatment or preservation, patient-specific ESCs or juvenile gonad is not available. We therefore aim to achieve in vitro spermatogenesis using male germline stem cells (GSCs) without the use of juvenile gonad. GSCs, when cultured on...

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PMID: 33176123
DOI: 10.1016/j.stemcr.2020.10.006

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