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Article

Human mesenchymal stem cells treatment improved hepatic lesions and reversed gut microbiome disorder in non-alcoholic steatohepatitis.

Aging - 8 Nov 2020

Yang Zhiyu, Xia Qiaoyun, Lu Di, Yue Han, Zhang Jianmin, Li Yalong, Zhang Bingyong, Li Xiuling, Cao Mingbo

Abstract excerpt

Effective therapies for non-alcoholic steatohepatitis (NASH) are urgently needed. We investigated the effect of human mesenchymal stem cells (hMSCs) on the intestinal flora in NASH treatment. We isolated the hMSCs from the umbilical cords and divided male C57BL/6 mice into three groups, namely, chow, methionine-choline-deficient (MCD), and MCD+hMSCs. After collecting the feces and liver of the mice, we evaluated...

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Identifiers

PMID: 33168782
DOI: 10.18632/aging.103962
PMCID: PMC7695425

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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