Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrative Analysis of miRNAs Identifies Clinically Relevant Epithelial and Stromal Subtypes of Head and Neck Squamous Cell Carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Feb 2021

Holt Jeremiah, Walter Vonn, Yin Xiaoying, Marron David, Wilkerson Matthew D, Choi Hyo Young, Zhao Xiaobei, Jo Heejoon, Hayes David Neil, Ko Yoon Ho

Abstract excerpt

PURPOSE: The objective of this study is to characterize the role of miRNAs in the classification of head and neck squamous cell carcinoma (HNSCC). EXPERIMENTAL DESIGN: Here, we analyzed 562 HNSCC samples, 88 from a novel cohort and 474 from The Cancer Genome Atlas, using miRNA microarray and miRNA sequencing, respectively. Using an integrative correlations method followed by miRNA expression-based hierarchical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cluster Analysis
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Regulatory Networks

Share to Head and Neck Neoplasms

Share to Kaplan-Meier Estimate

Share to MicroRNAs

Share to Risk Assessment

Share to Squamous Cell Carcinoma of Head and Neck

Source

Open in PubMed Open full text

Identifiers

PMID: 33148669
DOI: 10.1158/1078-0432.CCR-20-0557
PMCID: PMC7854517

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrative Analysis of miRNAs Identifies Clinically Relevant Epithelial and Stromal Subtypes of Head and Neck Squamous Cell Carcinoma.PMID 33148669Read ↗

Integrative miRNA Profiling Reveals Molecular Heterogeneity in Head and Neck Squamous Cell Carcinoma.Semantic proximity Read ↗

Integrative Analysis of Head and Neck Cancer Identifies Two Biologically Distinct HPV and Three Non-HPV SubtypesSemantic proximity Read ↗

Integrative Single-Cell and Bulk Transcriptomes Analyses Identify Intrinsic HNSCC Subtypes with Distinct Prognoses and Therapeutic VulnerabilitiesSemantic proximity Read ↗

Single‐cell sequencing of head and neck carcinoma: Transcriptional landscape and prognostic model based on malignant epithelial cell featuresSemantic proximity Read ↗

Comprehensive analysis of DNA damage repair in squamous cell carcinoma subtypes.Semantic proximity Read ↗

Clusterization in head and neck squamous carcinomas based on lncRNA expression: molecular and clinical correlatesSemantic proximity Read ↗

Subtyping of head and neck squamous cell cancers based on immune signatures.Semantic proximity Read ↗

Molecular Subtypes Based on Cell Differentiation Trajectories in Head and Neck Squamous Cell Carcinoma: Differential Prognosis and Immunotherapeutic Responses.Semantic proximity Read ↗

A multi-omics approach to identify prognostic subtypes and therapeutic targets in head and neck squamous cell carcinomaSemantic proximity Read ↗

Characteristic miRNA expression signature and random forest survival analysis identify potential cancer-driving miRNAs in a broad range of head and neck squamous cell carcinoma subtypesSemantic proximity Read ↗

A novel 3-miRNA network regulates tumour progression in oral squamous cell carcinomaSemantic proximity Read ↗

Tumor Subtype Classification Tool for HPV-associated Head and Neck CancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.