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Article

BRD4 and PIN1 gene polymorphisms are associated with high pulse pressure risk in a southeastern Chinese population.

BMC cardiovascular disorders - 4 Nov 2020

Qiu Jin-Jia, Yang Rui-Zhi, Tang Yi-Jie, Lin Ying-Yi, Xu Hao-Jie, Zhang Na, Liang Min, Cai Hong-da, Zeng Kai, Wu Xiao-Dan

Abstract excerpt

BACKGROUND: BRD4 and PIN1 have been described to be involved in inflammation and vascular endothelial cell dysfunction, which in turn may increase pulse pressure. HYPOTHESIS: Genetic mutations within the BRD4 and PIN1 genes could affect the risk of high pulse pressure. METHODS: A total of four single nucleotide polymorphisms (SNPs) (BRD4: rs4808278; PIN1: rs2233678, rs2287838, and rs2233682) were genotyped in a...

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Identifiers

PMID: 33148187
DOI: 10.1186/s12872-020-01757-x
PMCID: PMC7640679

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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